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The Actin Cytoskeleton and the Regulation of Cell Migration by Jonathan M. Lee (Paperback, 2013)

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About this product

Product Information

The mammalian cytoskeleton is an internal framework of actin, tubulin, and intermediate filament proteins. Proteins of these three classes assemble non-covalently into filamentous polymers that support the structural integrity of the relatively fragile lipid plasma membrane. In addition, cytoskeletal polymers provide the mechanical strength that hold a cell together and anchor it to its growth substrate. The cytoskeleton must also have the capacity for rapid and substantial remodeling and provide the motive and tractor force necessary to drive motility. As such, the cytoskeleton has a functional duality: sufficiently rigid to prevent plasma membrane deformation but pliable enough to allow for cytokinesis; sufficiently adhesive to allow for traction but dynamic enough to allow movement from one place to another. A major research challenge in cytoskeleton biology is to understand how cytoskeletal proteins assemble and dissemble in support of physiological processes. This chapter will focus on the role of the actin cytoskeleton in cell migration. More specifically, we will focus on the actin cytoskeleton of vertebrate cells.

Product Identifiers

Publisher
Morgan & Claypool Publishers
ISBN-13
9781615043880
eBay Product ID (ePID)
190059446

Product Key Features

Author
Jonathan M. Lee
Publication Name
The Actin Cytoskeleton and the Regulation of Cell Migration
Format
Paperback
Language
English
Subject
Biology
Publication Year
2013
Type
Textbook
Number of Pages
71 Pages

Dimensions

Item Height
235mm
Item Width
191mm
Item Weight
166g

Additional Product Features

Title_Author
Jonathan M. Lee
Series Title
Colloquium Series on Building Blocks of the Cell: Cell Structure and Function
Country/Region of Manufacture
United States

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