Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.
Product Identifiers
Publisher
Humana Press Inc.
ISBN-13
9781617790423
eBay Product ID (ePID)
106692449
Product Key Features
Author
Catherine J. Wu
Publication Name
Protein Microarray for Disease Analysis: Methods and Protocols
Format
Hardcover
Language
English
Subject
Chemistry, Biology
Publication Year
2011
Type
Textbook
Number of Pages
373 Pages
Dimensions
Item Height
254mm
Item Width
178mm
Volume
723
Item Weight
925g
Additional Product Features
Series Title
Methods in Molecular Biology
Country/Region of Manufacture
United States
Editor
Catherine J. Wu
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