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Death Receptors in Cancer Therapy by Wafik S. El-Deiry (Paperback, 2010)

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Product Information

An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

Product Identifiers

Publisher
Humana Press Inc.
ISBN-13
9781617374012
eBay Product ID (ePID)
104014161

Product Key Features

Author
Wafik S. El-Deiry
Publication Name
Death Receptors in Cancer Therapy
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
374 Pages

Dimensions

Item Height
254mm
Item Width
178mm
Item Weight
736g

Additional Product Features

Series Title
Cancer Drug Discovery and Development
Country/Region of Manufacture
United States
Editor
Wafik S. El-Deiry

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