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Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy by Matthias J. N. Junk (Hardback, 2011)

About this product

About this product

Product Information

In his thesis, Matthias Junk takes an invative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure - a consequence of the protein's adaptability to host various endogeus compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nascale. These heterogeneities bear consequences for the material's hosting properties and enable unforeseen complex catalytic functionalities.

Product Identifiers

Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg, Springer-Verlag Berlin and Heidelberg Gmbh & Co. K
ISBN-10
364225134x
ISBN-13
9783642251344
eBay Product ID (ePID)
111556385

Product Key Features

Author
Matthias J. N. Junk
Format
Hardback
Language
English
Subject
Chemistry
Type
Textbook

Dimensions

Weight
508g
Height
235mm
Width
155mm

Additional Product Features

Place of Publication
Berlin
Spine
18mm
Series Title
Springer Theses
Content Note
Biography
Date of Publication
31/12/2011
Genre
Chemistry
Country of Publication
Germany

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