After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Product Identifiers
Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
ISBN-13
9783540689607
eBay Product ID (ePID)
96285469
Product Key Features
Author
Harald H. H. w. Schmidt, Franz B. Hofmann, Johannes-Peter Stasch
Publication Name
Cgmp: Generators, Effectors and Therapeutic Implications
Format
Hardcover
Language
English
Subject
Medicine, Chemistry, Biology, Psychiatry
Publication Year
2008
Type
Textbook
Number of Pages
583 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Volume
191
Item Weight
1058g
Additional Product Features
Series Title
Handbook of Experimental Pharmacology
Country/Region of Manufacture
Germany
Editor
Johannes-Peter Stasch, Franz B. Hofmann, Harald H. H. w. Schmidt