Platelet size and count are associated with cardiac ischemia and ischemic stroke, two of the most common forms of acute cardiovascular disease. While platelet count (PC) is a common clinical measure, assessment of platelet size using mean platelet volume (MPV), the average size of platelets in a blood sample, and platelet distribution width (PDW), the variance of the platelet volume curve, are less frequently used. The overall objective of my research is to characterize these three quantitative platelet measures in a population of healthy individuals and evaluate the genetic and environmental determinants of these traits. Clinical and anthropometric predictors were examined in addition to a genome-wide association study (GWAS) conducted for each of these three quantitative platelet traits. 23 SNPs were associated at a suggestive level of significance (p
Product Identifiers
Publisher
Lap Lambert Academic Publishing
ISBN-13
9783659617522
eBay Product ID (ePID)
209036462
Product Key Features
Author
Bozzi Laura
Publication Name
Genetic and Environmental Determinants of Platelet Markers
Format
Paperback
Language
English
Subject
Biology
Publication Year
2014
Type
Textbook
Number of Pages
76 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
122g
Additional Product Features
Title_Author
Bozzi Laura
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