Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of likelihood-free methods of Bayesian inference for complex stochastic models. Re-written to reflect this modern perspective, this second edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. Keeping with the spirit of the first edition, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. New in the Second Edition All examples have been updated to Systems Biology Markup Language Level 3 All code relating to simulation, analysis, and inference for stochastic kinetic models has been re-written and re-structured in a more modular way An ancillary website provides links, resources, errata, and up-to-date information on installation and use of the associated R package More background material on the theory of Markov processes and stochastic differential equations, providing more substance for mathematically inclined readers Discussion of some of the more advanced concepts relating to stochastic kinetic models, such as random time change representations, Kolmogorov equations, Fokker-Planck equations and the linear noise approximation Simple modelling of extrinsic and intrinsic noise An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional mathematical detail and computational methods which will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.
Product Identifiers
Publisher
Taylor & Francis Inc
ISBN-13
9781439837726
eBay Product ID (ePID)
111556940
Product Key Features
Author
Darren J. Wilkinson
Publication Name
Stochastic Modelling for Systems Biology
Format
Hardcover
Language
English
Subject
Biology, Mathematics
Publication Year
2011
Type
Textbook
Number of Pages
363 Pages
Dimensions
Item Height
235mm
Item Width
156mm
Item Weight
658g
Additional Product Features
Title_Author
Darren J. Wilkinson
Series Title
Chapman & Hall/Crc Mathematical and Computational Biology